Exploring the facts
Diabetes is a disease wherein the body has trouble
regulating the level of sugar (glucose) in the bloodstream. In healthy
individuals, the pancreas produces a hormone called insulin, which works to
transport glucose molecules across cell membranes and into cells for energy
production.
In diabetics, depending on whether they suffer from the Type
1 or Type 2 form of the disease, the body is either unable to produce insulin,
or it’s unable to use it in a way that’s sufficient enough to maintain glucose
at a healthy level in the bloodstream. Irregular or unstable glucose levels can
cause a huge array of serious, life-threatening conditions, which we talk about
in detail in this article.
In regard to CBD oil for diabetes, there are two main things
to consider in order to determine the degree of viability that the drug may
have on the increasingly-prevalent disease:
MAJOR CONSIDERATIONS WHEN USING CBD OIL FOR DIABETES
WHAT TO CONSIDER?
In what ways (if any), does CBD work to improve either the
function and/or production of insulin?
In what ways might CBD work to alleviate the spectrum of
side effects caused by irregular blood sugar levels?
Here, in the hopes of shedding some light on why CBD oil for
diabetes has gained such popularity among patients and physicians alike, we
talk about recent research publications that have directly addressed both of
these questions.
Before Discussing CBD for Diabetes, What Even is the
Disease?
To elaborate on the rudimentary processes explained in the
introduction, diabetes is a disease wherein the body is unable to properly
transfer the glucose from food into energy sources for cells.
And of course, without energy sources, the body’s cells
(which are responsible for every functional mechanism of life) will be unable
to carry out the requisite pathways needed to survive.
“Without blood glucose regulation, cells are unable to carry
out requisite pathways needed for survival. Can CBD help to reverse the adverse
physiological effects of diabetes?”
In the case of Type 1 diabetics (who only make up about 5%
of the diabetic population), the body is no longer able to produce insulin,
which is the key hormone needed to transfer glucose molecules from the
bloodstream into cells. This is generally due to an autoimmune attack on the
pancreas – the organ responsible for the production of insulin. Type 1 diabetes
usually arises in children or young adults who contract a pancreas-attacking virus,
and other than perhaps a genetic predisposition, there are not many specific
risk factors.
Type 2 diabetes is a more complex form of the disease
wherein the body still produces insulin, but it either doesn’t produce enough
of it, or the cells become resistant to its physiological pathways. Either way,
the resulting effect is similar to that of Type 1 diabetes, wherein the
underlying issue is a general inability to control blood glucose.
Also, Type 2 diabetes is a far more prevalent form of the
disease; it is estimated to affect over 400 million people worldwide, or
between 90 and 95% of the total diabetic population.
Additionally, far more risk factors are associated with Type
2 diabetes than there are with Type 1. Several of the most prominent of these factors
include:
DIABETES RISK FACTORS:
Weight (obesity increases risk greatly)
High sugar diets (combined with inactivity)
Family history and genetics
Ethnicity (African-Americans, Hispanics, and American
Indians are especially susceptible, though the reason is unknown)
Age (people over 45
are far more likely to develop diabetes)
Conventional Treatment Methods for Diabetes (CBD Not
Included)
In both Type 1 and Type 2 diabetes, an inability for glucose
to be absorbed into the body’s cells results in it building up to dangerously
high levels in the bloodstream. This results in the severe, potentially
life-threatening symptoms that are most often associated with the disease. Some
of these symptoms include:
Heart and blood vessel disease
Nerve damage
Stroke
Kidney disease
Vision problems
In short, there aren’t many areas of the body that go
unaffected by the physiological detriments of diabetes, and unless the disease
is monitored closely on a daily basis, the average diabetic will have a
lifespan between 10 and 15 years shorter than the average person’s.
Fortunately, conventional medications have gotten to the
point where diabetics – if they keep track of their glucose levels rigorously
and maintain an appropriate diet – can lead a rather normal lifestyle.
Since they can’t produce it on their own, most Type 1
diabetics are prescribed insulin either in the form of shots that they have to
self-administer, or in the form of a pump which automatically monitors blood
glucose and injects the hormone as needed.
While these forms of treatment are state of the art, they’re
by no means 100% effective; even the most responsible of diabetics can find it
difficult to avoid the dangerous consequences of irregular glucose levels.
“Even state-of-the-art diabetes treatments are not 100%
effective in maintaining healthy blood glucose. How might CBD compare to
conventional treatment options?”
Not to mention, without top of the line health insurance,
treatments like insulin pumps are far too expensive for the average individual
to consider. Most, in fact, are resorted to pricking blood from their finger to
monitor sugar levels, and self-administering insulin shots through hypodermic
needles.
In the case of Type 2 diabetes, individuals who are able to
get by without having to take insulin shots will most likely be prescribed a
pharmaceutical drug like Metformin or Avandia, which aid in the ability to
properly regulate glucose.
However, as is far too common with these kinds of
prescription meds, a range of severe side effects is often produced, as is a
monthly medical bill that can be as cumbersome as the side effects themselves.
This is why many diabetics in recent years have been more
than willing to try alternative treatment options like CBD oil. Even if CBD can
replace just one of their prescription medications – or even reduce the
requisite doses – it’s generally more than worth it.
Not to mention, the general improvement in quality of life
for some diabetics that have added CBD to their treatment regimen has been, to
put it quite simply, pretty miraculous.
CBD Oil for Diabetes: What the Research has Shown
CBD Oil for Diabetes
As we mentioned earlier, in the world of medicine, anecdotal
evidence can only go so far. Regardless of the fact that many diabetics use CBD
oil every day of their lives to help manage their condition, most physicians
are wary to recommend it as a treatment because they can’t point to the exact
physiological reasons as to why it’s beneficial.
Fortunately, along with its potential to help with
cancer-related symptoms and nervous disorders, CBD for diabetes has been a
pretty well-researched area of medical cannabis.
Dr. Raphael Mechoulam, a research scientist from the Hebrew
University of Jerusalem, points to the fact that naturally-occurring CBD
receptors occur throughout the human body – from the brain and nervous tissues
to organs, endocrine glands, and immune cells.
And one of the organs where he’s found the receptors to be
highly prevalent? The pancreas.
“Naturally-occurring CBD receptors occur throughout the
human body: in the brain, nervous system, and crucially for sufferers of
diabetes – in the islet cells of the pancreas.”
In fact, endocannabinoid receptors (namely CB-1 receptors)
have been found specifically in the organ’s islet cells – the exact location
where insulin is produced. What’s more, it’s been suggested that the stimulus
of these receptors in the islet cells may have links to insulin production.
Now, regardless of how intriguing the research is, we are by
no means sitting here and saying that endocannabinoid receptors are directly
responsible for the production of insulin, or that CBD is a cure for diabetes
in any way shape or form. While it’s possible that the receptors may play a
crucial role in the production of insulin, much more research needs to be done
in order to pinpoint the physiological mechanisms and exact chemical pathways
that are responsible for doing so.
We will say, though, that preliminary studies on CBD for
diabetes have been so promising that it’s led to the American Journal of
Medicine’s Dr. Joseph Alpert to call on the DEA and the National Institute of
Health (NIH) for increased funding and collaboration on continued research.
Moreover, the National Organization for the Reform of
Marijuana Laws (NORML) has gone so far as to suggest that endocannabinoids may
be “the most important physiologic system involved in establishing and
maintaining human health,” based on their central role in regulating
homeostasis, which is the body’s ability to maintain normative operating
conditions in spite of harmful stimuli.
Can CBD Help Treat Underlying Symptoms of Diabetes?
What’s been even more concrete than research on CBD’s
potential role in insulin production, though, has been research on the
compound’s ability to help treat and prevent common medical conditions
associated with diabetes.
One of the most prominent factors associated with the
development of insulin resistance in Type 2 diabetes is chronic inflammation
related to obesity. The excessive presence of fatty tissue in obese Type 2
diabetics drastically limits the efficiency of glucose metabolism, which in
turn results in high levels of sugar building up in the bloodstream. The
specific anti-inflammatory properties of CBD, however, have long been known to
directly combat glucose metabolic disorders and improve overall metabolism.
“It is possible that the anti-inflammatory properties of CBD
may be able to provide side-effect free therapy for both Type-1 and Type-2
diabetes patients.”
Nerve damage is another condition commonly associated with
diabetes. In many instances, diabetics will have limited sensation in their
lower extremities, and in severe cases, amputations of the leg(s) are often
necessary. This is due to a lack of sufficient blood flow, which eventually
results in the breakdown of tissue and the increased risk for infection. CBD,
in turn, is a federally patented neuroprotectant and has been shown to reduce
infarcts (areas of dead tissue due to lack of blood flow) by up to 30%.
Likewise, there have been dozens of other publications that
have shown great promise in the role of CBD as a treatment for diabetes,
including studies on retinopathy (a disorder of the eyes) and diabetic
cardiovascular dysfunction.
In short, the medical potential and therapeutic benefits of
CBD oil for diabetes is nothing short of phenomenal; many diabetics use it
every day to treat the disease and improve their overall quality of life, and
thousands more will continue to do so in the future in light of increased
research and improved information.
Lastly, on a side note, it’s important to point out that CBD
oil will not get you high – unlike whole plant marijuana, it contains hardly
any THC, which is the cannabinoid responsible for the psychoactive properties
of the drug.
CBD Oil, Diabetes, and Harvard Health
In January 2018, Harvard Medical School’s Dr. Peter
Grinspoon referenced a Healthline article that reviewed the potential for
cannabis to decrease insulin resistance and improve blood sugar.
“Harvard Health researchers have discovered that marijuana
use may be able to decrease insulin resistance, and improve overall blood sugar
levels.”
In the article, which was the first of its kind to
“investigate the relationship between marijuana, glucose, and insulin
resistance,” it was pointed out that cannabis use can directly help regulate
blood sugar levels, waist size, and body mass index — three factors that are
crucial to both the prevention and control of Type-1 and Type-2 diabetes.
The study, which reviewed data from 4,657 patients over a
5-year period, determined a “significant link between the regular use of
marijuana and better blood sugar control,” and also noted that consistent
cannabis users displayed:
A 16% reduction in fasting insulin levels
A 17% decrease in insulin resistance levels
Increased levels of HDL-C
Smaller overall waist circumference (an implication of
reduced instances of obesity)
Final Thoughts on CBD, Diabetes, and Future Treatment
Options
CBD oils can range in terms of their overall concentrations
of the active cannabinoid; in other words, not all tinctures are the same, and
different dosages will likely be required depending on the specific oil that
you end up using (although the proper dosage should always be labeled on the
bottle).
“Researchers concluded that a ‘significant link’ exists
between the regular use of cannabis and better blood sugar levels.”
Likewise, CBD oil is no guaranteed solution for all diabetics; while some patients have found it highly therapeutic, it will ultimately be more effective for some individuals than it is for others. As is always the case, it’s important to do your own research, and if possible, speak with a professional about some possible tinctures that may be appropriate for you and your specific condition.
If you have questions or need more information, please shoot us an email or a phone call. In addition, please stop by our CBD Shop at 4607 Highway 146, Suite A in Baytown, Texas.
